genBart file for PROMISSE manuscript

Published: 6 July 2018| Version 1 | DOI: 10.17632/hg596dwdr6.1
Contributor:
Seunghee Hon

Description

We are submitting a manuscript and this R dataset is served as a supplementary data. In this study (PROMISSE), we longitudinally profiled the healthy and SLE blood transcriptome dynamics during and after pregnancy using microarray and flow cytometry. Matched non-pregnant healthy and SLE subjects were also recruited. To determine molecular signatures associated with healthy pregnancy, SLE pregnancy, and SLE-related pregnancy complications, linear mixed model analysis were performed on the microarray and flow cytometry and the results were combined into an R dataset that can be interactively uploaded and accessed through http://52.25.7.162/bart/. Users can access sample information, run statistics and generate transcriptional heatmaps and module maps interactively. Users can browse the mixed model and Q-gen analysis, as well as the flow cytometry results and can generate their own heatmaps and plots.

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Institutions

Weill Cornell Graduate School of Medical Sciences, Baylor Scott & White Health

Categories

Autoimmunity, Pregnancy, Systemic Lupus Erythematosus, Flow Cytometry, Microarray

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