Non-Hemolytic and Non-Toxic Antimicrobial Peptides Predicted from Omics Data of Cephalopods' Posterior Salivary Glands

Published: 18 September 2023| Version 1 | DOI: 10.17632/htntmccyd4.1
Guillermin Agüero-Chapin, Dany Domínguez-Pérez, Yovani Marrero-Ponce


This dataset compiles non-hemolytic and non-toxic antimicrobial peptides (AMPs) consistently identified within omics data extracted from Cephalopods' Posterior Salivary Glands (PSG). It consists of a non-redundant set of these AMPs, predicted across 13 non-hemolytic/non-toxic AMP datasets reported in (doi: 10.17632/ccp94tgcp2.1). These datasets were derived from agreed non-hemolytic/non-toxic predictions by several models, applied to AMP libraries resulting from the screening of enzymatically-digested proteins extracted from Cephalopods' PSG (doi: 10.17632/6fjsdnvygb.1). This dataset represents a valuable source of privileged AMPs for further exploration and drug discovery


Steps to reproduce

The creation of this dataset involved two key steps: 1. The initial peptide libraries, accessible via doi: 10.17632/ccp94tgcp2.1, were combined. 2. To eliminate sequence redundancy, CD-HIT was employed with a sequence identity threshold set at 0.98


Universidade do Porto Centro Interdisciplinar de Investigacao Marinha e Ambiental


Biodiscovery, Cephalopoda, Omics, Peptide Library, Antimicrobial