Raw Data on Genetic Variants and Muscular Fitness in a Follow-Up Study of Middle-Aged and Older Adults

Published: 5 August 2024| Version 1 | DOI: 10.17632/jcfjfh8ybk.1
Contributors:
,
,

Description

This dataset from a longitudinal study provides comprehensive anthropometric and physical fitness data from participants at baseline and 2.7 years later. It includes measurements of height (to the nearest 0.5 cm) and weight (to the nearest 0.1 kg) for calculating BMI. Physical fitness was assessed using isometric handgrip strength, lower body strength (30-second chair-stand test), functional mobility (timed up-and-go test), and aerobic endurance (6-minute walk test), all demonstrating acceptable reliability (ICC > 0.7) within the Kosovo population. Additionally, genotypes were obtained from saliva samples, focusing on single nucleotide polymorphisms (SNPs) in the VDR (rs7975232, rs2228570, rs731236) and GC (rs4588, rs2282679) genes. Vitamin D status was determined exclusively at the follow-up measurements and analyzed for total 25-(OH)D levels using an enzyme-linked immunosorbent assay. This dataset enables the exploration of the impact of genetic variants on muscle fitness and vitamin D status in middle-aged and older adults in Kosovo.

Files

Institutions

Universitat Wien Forschungsplattform Active Ageing, Universitat Wien Zentrum fur Sportwissenschaft und Universitatssport

Categories

Gerontology, Single Nucleotide Polymorphism, Vitamin D, Fitness, Healthy Ageing

Funding

University of Vienna

Research Platform Active Ageing

HERAS+

MPC-2022-05728

Licence