Dataset 8 - Non-redundant DRAMP and StarPepDB Databases, Including Sequences With Less Than 0.40 Similarity To Both Databases, And The Resulting Cnidaria Singular AMPs (CnSA)
Description
Compilation of the non-redundant (10 to 100 aminoacids) members of the DRAMP and StarPepDB databases used for the identification of Cnidaria Singular AMPs (CnSA) with a sequence identity below 0.40; the resulting peptides with less than 0.40 sequency identity with DRAMP and StarPepDB members; and the resulting 3,130 Cnidaria Singular Antimicrobial Peptides (CnSA).
Files
Steps to reproduce
1 - Pre-processing of the StarPepDB and DRAMP datasets by applying CD-HIT v4.8.1 (https://github.com/weizhongli/cdhit/releases) at 0.98 sequence identity and retaining AMPs between 10 and 100 AA. 2 - To identify unique antimicrobial peptides (AMP) from Cnidaria, we compared our non-redundant, non-haemolytic, and non-toxic composite dataset "Mendeley Data, V1, doi: 10.17632/dc5c6gb2w6.1" against two public AMP databases - StarPepDB (https://github.com/Grupo-Medicina-Molecular-y-Traslacional/StarPep/) and DRAMP (http://dramp.cpu-bioinfor.org/), using CD-HIT-2D v4.8.1 (https://github.com/weizhongli/cdhit/releases) at 0.40 identity cutoff 3 - Cnidarian AMPs were considered singular if their sequence identity with StarPepDB and DRAMP members was below 0.40 4 - Cnidaria Singular AMPs (CnSA) were obtained by the union dataset of the members with less than 0.40 sequence identity with StarPepDB and DRAMP members