FRETsg: Biomolecular structure model building from multiple FRET experiments

Published: 15 April 2004| Version 1 | DOI: 10.17632/jjkrsvhh5v.1
G.F. Schröder, H. Grubmüller


Abstract Fluorescence energy transfer (FRET) experiments of site-specifically labelled proteins allow one to determine distances between residues at the single molecule level, which provide information on the three-dimensional structural dynamics of the biomolecule. To systematically extract this information from the experimental data, we describe a program that generates an ensemble of configurations of residues in space that agree with the experimental distances between these positions. Furthermore,... Title of program: FRETsg Catalogue Id: ADTU_v1_0 Nature of problem Given an arbitrary number of distances distributions between an arbitrary number of points in three-dimensional space, find all configurations (set of coordinates) that obey the given distances. Versions of this program held in the CPC repository in Mendeley Data ADTU_v1_0; FRETsg; 10.1016/j.cpc.2004.02.001 This program has been imported from the CPC Program Library held at Queen's University Belfast (1969-2018)



Molecular Biology, Physical Chemistry, Molecular Physics, Biological Sciences, Computational Physics