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- Data for: Early life social experience adjusts adulthood fear extinction deficit and associated dopamine profile abnormalities in a rat model of PTSDData in brief
- Dataset
- Data for: Meta-analyses of the functional neural alterations in subjects with Internet gaming disorder: similarities and differences across different paradigmscoordinate and results of meta-analysis
- Dataset
- Data for: Carbamoylated erythropoietin induces a neurotrophic gene profile in neuronal cellsBioanalyzer analysis
- Dataset
- Data for: Cognitive impairment in first-episode drug-naïve patients with schizophrenia: relationships with serum concentrations of brain-derived neurotrophic factor and glial cell line-derived neurotrophic factorcognitive function
- Dataset
- datset related to article "Psychiatric autoimmune conditions in children and adolescents: Is catatonia a severity marker"xls dataset with clinical data of patient involved in the study at title
- Dataset
- Childhood maltreatment history for guiding personalized antidepressant choice in major depressive disorder: Preliminary results from a systematic reviewChildhood maltreatment history for guiding personalized antidepressant choice in major depressive disorder: Preliminary results from a systematic review Childhood maltreatment (CM) is a predictor of poor outcome across treatments for major depressive disorder (MDD), while its potential role as a predictor of differential responses to specific antidepressants has received little attention. The present systematic review examined pharmacological studies (published up to June 30th, 2020) that included head-to-head comparisons of antidepressant treatments among adult MDD patients with a reported history of CM or no history to evaluate if CM may help clinicians choose antidepressants with greatest likelihood of successful outcome. Only three studies were included, providing limited and provisional results. These preliminary findings suggest that sustained-release bupropion (alone or in combination) or aripiprazoleaugmentation as next-step intervention did not demonstrate differential outcome among MDD patients with or without a history of childhood adversity. Further, sertraline and the group of antidepressants with low affinity for the serotonin transporter may be less suitable for MDD patients with childhood abuse history than escitalopram, venlafaxine-XR, or antidepressants with high affinity for the serotonin transporter. The critical question of the most potentially efficacious treatment regimens for adult MDD with CM history requires further large-sample studies involving a greater number of medications, specifically designed to analyse the moderating effects of different types of CM, and possibly including objective biomarkers.
- Dataset