Bioorganic & Medicinal Chemistry Letters
ISSN: 0960-894X
Datasets associated with articles published in Bioorganic & Medicinal Chemistry Letters
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- Data for: Ultra-potent vinblastine analogues improve on-target activity of the parent microtubulin-targeting compoundSupporting Information
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- Data for: Austalides V and W, New Meroterpenoids from the Fungus Aspergillus ustus and Their Anti-Cancer ActivitiesThis research is dedicated to the isolation and determination of the structure of two new metabolites (austalides V and W) from the austalide meroterpenoids and the study of their anticancer activity. The structures of novel metabolites were established by modern physical methods (multinuclear NMR and mass-spectrometry) and by comparison with related known compounds. The main structural feature of both compounds is a five-membered cycle (G), an unprecedented structural fragment, first found in austalides.
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- Data for: Synthesis and Evaluation of 1,3,5-triazine Derivatives as Sunscreens Useful to Prevent Skin CancerSupplementary material
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- Data for: Addition of ethylamines to the phenols of bithionol and synthetic retinoids does not elicit activity in gram-negative bacteriaSupporting information for the article "Addition of ethylamines to the phenols of bithionol and synthetic retinoids does not elicit activity in gram-negative bacteria" by Wuest et al.
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- Data for: An Anthrone-Based Kv7.2/7.3 Channel Blocker with Improved Properties for the Investigation of Psychiatric and Neurodegenera-tive DisordersAssay protocols; synthetic protocols; characterization data for compounds
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- Data for: Identification of a novel allosteric GLP 1R antagonist HTL26119 using structure- based drug designDiscovery of antagonists of GLP-1R by structure based drug design as exemplified by HTL26119
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- Data for: Discovery of piperazic acid peptide deformylase inhibitors with in vivo activity for respiratory tract and skin infectionsSupporting information for discovery of piperazic acid peptide deformylase inhibitors with in vivo activity for respiratory tract and skin infections
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- Data for: 2,4,5-Tris(alkoxyaryl)imidazoline derivatives as potent scaffold for novel p53-MDM2 interaction inhibitors: design, synthesis, and biological evaluationData for: 2,4,5-Tris(alkoxyaryl)imidazoline derivatives as potent scaffold for novel p53-MDM2 interaction inhibitors: design, synthesis, and biological evaluation
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- Data for: Rifamycin derivatives active against pathogenic rapidly-growing mycobacteriaMIC and Zone of inhibition data for a series of C25 Carbamate derivatives against a panel of clinical isolates of RGM including Mycobacterium abscessus
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- Data for: Design, synthesis and biological evaluation of novel HIV-1 protease inhibitors with pentacyclic triterpenoids as P2-ligandsThe data contents 1H NMR, 13C NMR and HRMS of all the target compounds.
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