Spatiotemporal organization of the E. coli transcriptome: Translation-independence and engagement in regulation

Published: 28 Jul 2019 | Version 1 | DOI: 10.17632/jpndmsc3c7.1
Contributor(s):

Description of this data

We found that a significant portion of E. coli transcriptome is asymmetrically distributed. Inhibition of translation did not alter the distribution pattern of many mRNAs. sRNAs accumulated at cell poles during envelope stress. We demonstrated that localization of sRNAs was mediated by HFq. Mutations in Hfq that affected its binding with sRNA or their mRNA target did not disrupt its redistribution at cell poles during envelope stress. Genomic loci encoding membrane transcript bglF favored its localization to membrane.

Experiment data files

Latest version

  • Version 1

    2019-07-28

    Published: 2019-07-28

    DOI: 10.17632/jpndmsc3c7.1

    Cite this dataset

    Kannaiah, Shanmugapriya (2019), “Spatiotemporal organization of the E. coli transcriptome: Translation-independence and engagement in regulation”, Mendeley Data, v1 http://dx.doi.org/10.17632/jpndmsc3c7.1

Statistics

Views: 1107
Downloads: 282

Categories

Messenger RNA, Fluorescence Imaging, Subcellular Localisation

Licence

CC BY 4.0 Learn more

The files associated with this dataset are licensed under a Creative Commons Attribution 4.0 International licence.

What does this mean?
You can share, copy and modify this dataset so long as you give appropriate credit, provide a link to the CC BY license, and indicate if changes were made, but you may not do so in a way that suggests the rights holder has endorsed you or your use of the dataset. Note that further permission may be required for any content within the dataset that is identified as belonging to a third party.

Report