Supplementary datasets and R scripts for: "Image-based Screen Capturing Misfolding Status of Niemann-Pick type C1 Identifies Potential Candidates for Chaperone Drugs"

Published: 16 September 2020| Version 3 | DOI: 10.17632/jr23ccpp46.3
Contributors:
Ryuta Shioi,
Fumika Karaki,
Hiromasa Yoshioka,
Tomomi Noguchi-Yachide,
Minoru Ishikawa,
Kosuke Dodo,
Mikiko Sodeoka,
Yuichi Hashimoto,
Kenji Ohgane

Description

Supplementary datasets and R scripts for "Image-based Screen Capturing Misfolding Status of Niemann-Pick type C1 Identifies Potential Candidates for Chaperone Drugs". This dataset contains; - Raw data and R script for colocalization analysis - An example R script and an example dataset for the quantification of Filipin staining assay. - An example R script and an example dataset for the image-based NPC1 chaperone screen. - Raw, uncropped gel images used in the accompanying manuscript. - Quantitative data used to prepare plots presented in the manuscript, including the processed screening result (as a data table).

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Institutions

Tokyo Daigaku Teiryo Seimei Kagaku Kenkyujo, RIKEN Global Research Cluster

Categories

Screening, Image Analysis

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