Exploring tear biomarkers with shotgun proteomics for retinoblastoma diagnosis
Description
Data contain accesion numbers and full description of proteins identified in tears comparing retinoblatoma subjects and healthy controls.
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The proportion of each protein was calculated by dividing the mean of protein abundance from retinoblastoma patients by their corresponding proteins of health individual controls. A logarithm base 2 to fold change (Y-axis) as well as a negative logarithm base 10 (x-axis) to the p-value (≥0.05) was applied to remove skewness and improve visibility of the plot. Some of the identified proteins were excluded as they are quite possibly present because a source of contamination such as keratins. We set a coefficient of variation equal or less than 0.2, an ANOVA test (P ≤0.05) as well as Bonferroni correction was performed.
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Consejo Nacional de Humanidades, Ciencias y Tecnologías
CF-G338 and CBF2023-2024-2470