Data for: Corticosterone and pyridostigmine/DEET exposure attenuate peripheral inflammation in a mouse model of Gulf War Illness: supporting a role for neuroinflammation.

Name: Data for: Corticosterone and pyridostigmine/DEET exposure attenuate peripheral inflammation in a mouse model of Gulf War Illness: supporting a role for neuroinflammation.
Creator: James O'Callaghan
Published: 2018-12-24T11:40:12.336Z
Keywords: Animal Models in Neurobiology, Enzyme-Linked Immunosorbent Assay, Real-Time Polymerase Chain Reaction, Gulf War

O'Callaghan, James; Miller, Julie; Miller, Diane; Lasley, Stephen; Barnes, Zachary; Michalovicz, Lindsay; Klimas, Nancy; Kelly, Kimberly; Morris, Mariana; Locker, Alicia; Fletcher, Mary Ann

doi:10.17632/k7m2swnw6s.1

Data for: Corticosterone and pyridostigmine/DEET exposure attenuate peripheral inflammation in a mouse model of Gulf War Illness: supporting a role for neuroinflammation.

Published: 24 December 2018| Version 1 | DOI: 10.17632/k7m2swnw6s.1

Contributors:

James O'Callaghan, Julie Miller, Diane Miller, Stephen Lasley, Zachary Barnes, Lindsay Michalovicz, Nancy Klimas, Kimberly Kelly, Mariana Morris, Alicia Locker, Mary Ann Fletcher

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RT-PCR of liver and Multiplex ELISA of serum cytokines/chemokines mRNA and protein, respectively. This data is collected from a GWI mouse model (see O'Callaghan et al., 2015), where mice received daily injections of a combination of PB and DEET for 14 days. On day 8, mice also received corticosterone in the drinking water for a total of 7 days. On day 15, the mice received a single injection of the sarin surrogate, DFP.

Data for: Corticosterone and pyridostigmine/DEET exposure attenuate peripheral inflammation in a mouse model of Gulf War Illness: supporting a role for neuroinflammation.

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