Data for: In vitro effects of Ganoderma lucidum spore oil on apoptosis in breast cancer cells—Cell viability assay and FACS analyses data

Published: 14 October 2019| Version 1 | DOI: 10.17632/kjrcc7phn9.1
Yizhen Xie, Huijia Liang, Jiaming Chen, Hao Yun, Jieyi Li, Xupeng Tan, Chunyan He, Xiaowei Ma, Wang Chen, Chunwei Jiao,


The mushroom Ganoderma lucidum (G. lucidum) is a traditional Chinese medicine reported to have a variety of pharmacological properties, including anti-cancer activity[1,2]. G. lucidum spore oil (GLSO) is a lipid substance extracted from sporoderm-broken spore of G. lucidum. Here, Data were provided on the effect of GLSO on apoptosis in breast cancer cells in vitro. As model systems, 4T1, MCF-7 and MDA-MB-231 breast cancer cell lines were used to verify the effect of GLSO on breast cancer cell proliferation. The cells were treated with various concentrations of GLSO (0.2, 0.4 and 0.6 μL/mL) for different time intervals (24, 48 and 72 hours), and measured cell viability was assessed by Trypan blue staining. Further, The results of early apoptosis and late apoptosis of MDA-MB-231 cells induced by GLSO (0.2, 0.4 and 0.6 μL/mL) for different time intervals (24 and 48 hours) in vitro by fluorescence activated cell sorting (FACS) analysis. This data article is part of a study Jiao et al., 2019 Jun, where detailed interpretation and discussion can be found.



Biological Sciences, Breast Cancer, Biocontrol in Food