Novel drug-like RAR-Beta agonist induces BRCA1 to prevent neuropathic pain

Published: 12 September 2019| Version 3 | DOI: 10.17632/kjvs5vgkbf.3
Contributors:
marco mendoza,
Maria Goncalves,
Jonathan Corcoran

Description

Differential gene expression analysis (RNA-sequencing) assessed in the SC from L5-SNL rats and non-injured rats, treated with vehicle or C286. Raw counts per gene (Raw counts.zip file) were normalized (quantile normalization; Normaliez counts.zip), then used for a differential gene expression analysis relative to the sample non-injured + vehicle (Diff_expression_DESeq2.zip). In addition, we have included herein a supplementary Table containing Gene Ontology (GO) terms per gene co-expression paths issued from the differential expression analysis. Notice that GO terms are described by their confidence of enrichment, expressend on "-10*log10(p-value).

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