debulkings Catharina Cancer Centre and adherent region January 2010 and July 2018

Published: 28 January 2020| Version 1 | DOI: 10.17632/kmmzvb93y4.1
Dorry Boll,


Introduction Centralization of cytoreductive surgery for ovarian cancer has shown to improve complete debulking rates. Some 30-35% percent of cytoreductive surgery encompasses bowel surgery and in the Netherlands these procedures are performed by the GI surgeon. In an effort to further increase the complete debulking rate, we created dedicated teams with a gynecological oncologist and a GI surgeon. Materials and Methods Data from treatment of epithelial ovarian cancer (EOC) diagnosed in the Netherlands in the province of Brabant between January 2010 and July 2018, were identified from the Netherlands Cancer Registry. Surgical outcomes were extracted from the period before centralisation and after centralisation and were compared using the t-test, χ2- test and logistic regression. Results Both complete primary cytoreductive surgery (from 77% to 85%, p=0.27) and complete interval cytoreductive surgery (from 71% to 77%, p=0.53) increased. Postoperative complications requiring re-intervention were similar, number of complications without re-intervention increased. The mortality did not change over time (30-day 0.7% versus 1.9%; p= 0.26 and 90-day 1.0% versus 3.1%; p= 0.11).



Catharina Ziekenhuis


Ovarian Cancer, Gynecological Cancer, Abdominal Surgery, Surgeon