Arduino based intra-cerebral microinjector device for neuroscience research.

Published: 30 May 2022| Version 1 | DOI: 10.17632/m77h37dfjf.1
Contributor:
Jorge Bravo-Martinez

Description

Stereotaxic surgery is a less invasive form of surgery that uses a three-dimensional coordinate system to place instruments at a specific location on the brain. Through this type of surgery, you can place: among others, needles within the structures of the brain, and therefore it can be done injections to deliver substances that otherwise could not cross the hematoencephalic barrier. The two most important parameters of the microinjection to control are, volume, and speed. The volume should not be so large that it displaces the brain tissue and tears it. The injection speed must also be slow so that the liquid that comes out of the syringe can diffuse into the tissue without displacing it and damaging it. Thus, the objectives of the present work are: 1) Develop not a 3D printed prototype but an end-user device. 2) It must be for animal research. 3) That It has the same precision in volume and speed as commercial devices. 4) That can be adjusted to 0.5 microliters to 1 ml microsyringes. 5) It can be placed directly on the stereotaxic surgery apparatus or used outside of it. 6) That the price is substantially lower than the commercial ones.

Files

Institutions

Universidad Nacional Autonoma de Mexico

Categories

Physiology, Neuroscience, Animal Physiology, Cellular Physiology, Microfluidics

License