Simulated patterns of CCM tube formation

Published: 26 June 2020| Version 1 | DOI: 10.17632/mbh97cgss3.1
Denis Tsygankov


This set includes 100 images of endothelial formations simulated with a model that allows for generating a range of different multicellular patterns depending on two biomechanical characteristics: the stability of cell-cell contacts and the strength of cell-matrix adhesion (Chernaya O, Zhurikhina A, Hladyshau S, Pilcher W, Young KM, Ortner J, Andra V, Sulchek TA, Tsygankov D. 2018. Biomechanics of Endothelial Tubule Formation Differentially Modulated by Cerebral Cavernous Malformation Proteins. iScience 9:347-358.)