Data for: Regulation of hyaluronan biosynthesis and clinical impact of excessive hyaluronan production

Published: 20-03-2018| Version 1 | DOI: 10.17632/mcw3bhc4yn.1
Paraskevi Heldin,
Chun-Yu Lin,
Spyridon Skandalis,
Yen-Hsu Chen,
Konstantinos Kolliopoulos


This review addresses the molecular mechanisms that regulate hyaluronan biosynthesis at both transcriptional and posttranslational levels, as well as the roles of hyaluronan deficiency or overproduction in various diseases, such as multiple myeloma, aggressive breast carcinomas, metabolic diseases and virus infection. Such knowledge may be use to devise methods for diagnosis or treatment of diseases.