Data for: NEUROENDOCRINE HYPERPLASIA IN A LARGE COMPOSITE ADENOMA- MICROCARCINOID Case Report and Literature Review on Colonic Adenoma-Microcarcinoids/Carcinoids.

Published: 22 February 2018| Version 1 | DOI: 10.17632/mfcnnxmwp3.1
Paulo Gonzalez, Justin Kelly, George Nassif, Tien Ahn Tran


A composite adenoma-microcarcinoid is an intestinal neoplasm consisting of intermixed adenomatous and well-differentiated neuroendocrine components. Although subtle neuroendocrine differentiation is commonly seen in intestinal adenomas, colorectal tumors containing a significant percentage of morphologically recognizable neuroendocrine cells are uncommon. Unlike other mixed endocrine-glandular colorectal neoplasms, which are generally malignant, the glandular component of a composite adenoma-microcarcinoid is histologically benign, with a natural history that is generally favorable. We report an unusually large tubular adenoma associated with a microcarcinoid that arises in a backdrop of neuroendocrine hyperplasia, a rare phenomenon that has not been well documented in the literature.



Pathology, Gastrointestinal Carcinoid Tumor, Gastrointestinal Cancer, Gastrointestinal Surgery, Neuroendocrine Tumor