Mortality and potential years of life lost attributable to poor glycemic control in Emiratis with diabetes

Published: 12 August 2019| Version 1 | DOI: 10.17632/mj94yydtmn.1
Contributors:
Saif Al-Shamsi,
Romona D. Govender,
Elpidoforos S. Soteriades

Description

The aim of this study was to estimate the fraction of deaths and potential years of life lost (PYLL) attributable to non-optimal HbA1c control among Emirati men and women with diabetes in the United Arab Emirates (UAE). This study was conducted in outpatient clinics at a tertiary care center in Al-Ain, UAE, between April 2008 and September 2018. The sample comprised of 583 adult UAE nationals, aged ≥ 18 years, with diabetes. Non-optimal HbA1c control was defined as HbA1c ≥ 6.5% and all-cause mortality was defined as death from any cause. At the end of the 9-year follow-up period, 86 (14.8%) participants died. Overall, up to 33% (95% confidence interval [CI], 2% to 63%) of deaths were attributable to non-optimal HbA1c control among patients with diabetes mellitus (DM). Stratified by sex, the adjusted fraction of avoidable mortality was 17% (95% CI, -23% to 57%) for men and 50% (95% CI, 3% to 98%) for women. Both deaths and PYLL attributable to non-optimal HbA1c control were higher in women compared to men. Up to one-third of all deaths in adult UAE nationals with DM could be attributed to non-optimal HbA1c control.

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