The Ashkenazi-centric G334R variant of p53 is severely impaired for transactivation but retains tumor suppressor function in a mouse model

Published: 10 October 2024| Version 1 | DOI: 10.17632/n72cxhtmg4.1
Contributors:
,
, Maureen Murphy

Description

The data from "The Ashkenazi-centric G334R variant of p53 is severely impaired for transactivation but retains tumor suppressor function in a mouse model" is represented here in its entirety. This includes all uncut scanned films of Western blots (including BMH crosslinking and Co-IP). This includes all microscopy images taken for Proximity Ligation Assay. This includes excel and prism files that were used to quantify and analyze Western Blots (densitometry), Proximity Ligation Assay microscopy images, RT-qPCR, CHip-qPCR, the mouse Cancer Incidence Curve, and all mouse logs. The raw and processed data for the RNA sequencing can be found with the following GEO accession number: GSE277585. The raw and processed data for the CHiP sequencing can be found with the following GEO accession number: GSE277586.

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Categories

RNA Sequencing, Confocal Microscopy, Western Blot

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