Data for: Practical bioinformatic DNA-sequencing pipeline for detecting oncogene amplification and EGFRvIII mutational status in clinical glioblastoma samples

Published: 15 Apr 2019 | Version 1 | DOI: 10.17632/nh5y2dddd2.1

Description of this data

Dataset 1. Sequencing and z-score normalized data results from reference and CNS samples. (A and B) Reference population coverage with means and standard deviations used to calculate z-scores shown at the top. Amplicon z-scores and followed by gene z-scores (A) and EGFRvIII z-scores (B) used to identify focal gene amplification (z-score > 5, final column in A) and EGFRvIII (z-score > 10, final column in B), respectively (EGFR.d2.7 = EGFRvIII).

Dataset 2. Reference values used to calculate amplicon and EGFRvIII z-scores from raw coverage matrix and sample metadata. For complete and actively updated repository that uses this reference data, refer to https://github.com/Michael-L-Miller/CoveRageAnalysis (doi:10.5281/zenodo.1220399).

Experiment data files

This data is associated with the following publication:

Practical Bioinformatic DNA-Sequencing Pipeline for Detecting Oncogene Amplification and EGFRvIII Mutational Status in Clinical Glioblastoma Samples

Published in: The Journal of Molecular Diagnostics

Latest version

  • Version 1

    2019-04-15

    Published: 2019-04-15

    DOI: 10.17632/nh5y2dddd2.1

    Cite this dataset

    Miller, Michael; Waluszko, Aneta; Tome-Garcia, Jessica; Sidorenko, Tatyana; Ye, Fei; Tsankova, Nadejda (2019), “Data for: Practical bioinformatic DNA-sequencing pipeline for detecting oncogene amplification and EGFRvIII mutational status in clinical glioblastoma samples”, Mendeley Data, v1 http://dx.doi.org/10.17632/nh5y2dddd2.1

Statistics

Views: 52
Downloads: 1

Categories

Neuro-Oncology, Neuropathology, Molecular Diagnostics

Licence

CC BY 4.0 Learn more

The files associated with this dataset are licensed under a Creative Commons Attribution 4.0 International licence.

What does this mean?
You can share, copy and modify this dataset so long as you give appropriate credit, provide a link to the CC BY license, and indicate if changes were made, but you may not do so in a way that suggests the rights holder has endorsed you or your use of the dataset. Note that further permission may be required for any content within the dataset that is identified as belonging to a third party.

Report