Data for: Practical bioinformatic DNA-sequencing pipeline for detecting oncogene amplification and EGFRvIII mutational status in clinical glioblastoma samples
Description of this data
Dataset 1. Sequencing and z-score normalized data results from reference and CNS samples. (A and B) Reference population coverage with means and standard deviations used to calculate z-scores shown at the top. Amplicon z-scores and followed by gene z-scores (A) and EGFRvIII z-scores (B) used to identify focal gene amplification (z-score > 5, final column in A) and EGFRvIII (z-score > 10, final column in B), respectively (EGFR.d2.7 = EGFRvIII).
Dataset 2. Reference values used to calculate amplicon and EGFRvIII z-scores from raw coverage matrix and sample metadata. For complete and actively updated repository that uses this reference data, refer to https://github.com/Michael-L-Miller/CoveRageAnalysis (doi:10.5281/zenodo.1220399).
Experiment data files
This data is associated with the following publication:
Cite this dataset
Miller, Michael; Waluszko, Aneta; Tome-Garcia, Jessica; Sidorenko, Tatyana; Ye, Fei; Tsankova, Nadejda (2019), “Data for: Practical bioinformatic DNA-sequencing pipeline for detecting oncogene amplification and EGFRvIII mutational status in clinical glioblastoma samples”, Mendeley Data, v1 http://dx.doi.org/10.17632/nh5y2dddd2.1
The files associated with this dataset are licensed under a Creative Commons Attribution 4.0 International licence.