LiP-SMap screen

Published: 4 January 2018| Version 1 | DOI: 10.17632/nhsktkcs3d.1
Ilaria Piazza


Supplementary analyzed data from Manuscript: TITLE: A map of protein-metabolite interactions reveals principles of chemical communication. JOURNAL: CELL. Article Type: Resource Article First Author: Ilaria Piazza Authors: Ilaria Piazza, Karl Kochanowski, Valentina Cappelletti, Tobias Fuhrer, Elad Noor, Uwe Sauer, Paola Picotti. Corresponding Author: Paola Picotti FILE: Piazza_SupplDataS8: Supplementary_DataAnalysis_S8. Related to Figure 6 and S6. Differential SEC-MS elution profiles upon ATP binding of ATP binding proteins undergoing large structural changes found by LiP-SMap. FILE: Piazza_SupplDataS9: Supplementary_DataAnalysis_S9. Related to Figure S6. Differential SEC-MS elution profiles upon ATP binding of proteins that do not bind ATP. FILE: Piazza_SupplDataS10: Supplementary_DataAnalysis_S10. Related to Figure 7. Concentration dependent local structural response curves relative to single conformotypic peptides.



Eidgenossische Technische Hochschule Zurich Institut fur Biochemie


Mass Spectrometry, Drugs, Proteomics, Biomarkers, Allosteric Regulation, Cell Metabolism, Metabolite, Metabolism, Allostery, Proteolysis, Drug Interaction, Ligand Binding, Small Molecules, Drug Design of Small Molecule, Interactome, Ligand Binding Domain, Chemogenomics, Metabolome