Postbiotics
Description
Complementary materials of: Evaluating the Efficacy of Saccharomyces boulardii ABB S3 and Kluyveromyces marxianus ABB S8 in Gastrointestinal Symptomatology Reduction Jordi Cuñé Castellana 1, Maria Tintoré Gazulla 2 Carlos de Lecea Flores de Lemus3 and Agustí Martí Gil 4 Citation: To be added by editorial staff during production. Academic Editor: Firstname Lastname Received: date Revised: date Accepted: date Published: date Copyright: © 2023 by the authors. Submitted for possible open access publication under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). 1 Affiliation 1; e-mail@e-mail.com 2 Affiliation 2; e-mail@e-mail.com * Correspondence: e-mail@e-mail.com; Tel.: (optional; include country code; if there are multiple corresponding authors, add author initials) Abstract: This study investigates the impact of a whole-yeast postbiotic, which includes the specific strains Saccharomyces boulardii ABB S3 and Kluyveromyces marxianus ABB S8, on the overall well-being of the gastrointestinal system. The study was carried out in a group of 17 healthy individuals who were experiencing gastrointestinal discomfort. These participants were administered a postbiotic capsule on a daily basis for a duration of one month. Outcomes were measured using symptomatic ratings, microbiota testing, and psychological measures. The findings demonstrated a significant improvement in gastrointestinal symptoms, as seen by a decrease in the average digestive distress score from 4.61 to 1.79. Additionally, there was an observed augmentation in the abundance of beneficial gut flora, indicating an improvement in gut health. The participants experienced an enhanced quality of life, accompanied by decreased levels of anxiety and somatization. During the baseline visit, their dietary habits were assessed and revealed increased consumption of non-recommended items, straying from the conventional Spanish eating patterns. The treatment successfully relieved many gastrointestinal problems and positively modified the composition of gut bacteria, resulting in enhanced quality of life and psychological well-being. The strong adherence and safety records indicate the possibility of wider use, while additional study is required to validate these results.