Data for: Comparative proteomics of geographically distinct saw-scaled viper (Echis carinatus) venoms from India

Published: 23-06-2020| Version 1 | DOI: 10.17632/nwd9m2t8v5.1
Karthikeyan Vasudevan


We investigated on venom variation in geographically distinct populations of Echis carinatus from three ecologically distinct regions: Tamil Nadu (ECVTN), Goa (ECVGO), and Rajasthan (ECVRAJ). Venom was fractionated by RP-HPLC, combined with SDS-PAGE, and subjected to tandem mass spectrometry. Toxins were identified, and their relative abundance was estimated. Using NCBI database of Echis genus, we queried the MS/MS spectra, and found 87, 44 and 48 proteins, in ECVTN, ECVGO and ECVRAJ respectively, belonging to 7-9 different toxin families. The differences in the venom profiles were due to change in the relative composition of the toxin families.