Data for: Comparative proteomics of geographically distinct saw-scaled viper (Echis carinatus) venoms from India

Published: 23 June 2020| Version 1 | DOI: 10.17632/nwd9m2t8v5.1
Karthikeyan Vasudevan


We investigated on venom variation in geographically distinct populations of Echis carinatus from three ecologically distinct regions: Tamil Nadu (ECVTN), Goa (ECVGO), and Rajasthan (ECVRAJ). Venom was fractionated by RP-HPLC, combined with SDS-PAGE, and subjected to tandem mass spectrometry. Toxins were identified, and their relative abundance was estimated. Using NCBI database of Echis genus, we queried the MS/MS spectra, and found 87, 44 and 48 proteins, in ECVTN, ECVGO and ECVRAJ respectively, belonging to 7-9 different toxin families. The differences in the venom profiles were due to change in the relative composition of the toxin families.



Mass Spectrometry, Snake, Reverse Phase High Performance Liquid Chromatography, Envenomation, Proteome Analysis, Venom