Combined ionizing radiation exposure by gamma-rays and carbon-12 nuclei increased neurotrophic factors content and prevent age-associated decrease in the sensorimotor cortex volume of rats
Published: 22 April 2024| Version 1 | DOI: 10.17632/nwj854ppyd.1
Contributor:
Viktor KokhanDescription
Here, we studied the effect of combined ionizing radiation exposure (0.4 Gy γ-rays and 0.14 Gy carbon-12 nuclei) on the locomotor and exploratory activity of Wistar rats, as well as assessed the sensorimotor cortex volume by magnetic resonance imaging-based morphometry at 1 week and 7 months post-irradiation. The sensorimotor cortex tissues were processed to determine whether the behavioral and morphologic effects were associated with changes in neurotrophins content.
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Institutions
Federal'nyj medicinskij issledovatel'skij centr psihiatrii i narkologii imeni V.P.Serbskogo
Categories
Neuroscience, Neurotrophic Factor, Ionizing Radiation, Morphometry, Cosmic Ray