Dataset for MIO: microRNA target analysis system for immuno-oncology
The MIO (MicroRNA Target Analysis System for Immuno-Oncology) dataset is a vital resource for immuno-oncology research. It offers 40 microRNA target prediction tools, curated immune-related gene and microRNA signatures, and processed TCGA data, including estimates of immune cell infiltration and the immunophenoscore. This dataset facilitates in-depth investigations into microRNA regulation, immune responses, and the immunophenotype of various cancer types, aiding the development of novel immuno-oncological insights and therapeutic strategies.
Steps to reproduce
To understand the process of obtaining integration from 40 microRNA/Gene target databases and accessing the datasets in this repository, please refer to the supplementary materials provided in the MIO publication. You can find the publication using the DOI: 10.1093/bioinformatics/btac366.