Gastrodia elata Blume extract improves high-fat diet-induced type 2 diabetes by regulating gut microbiota and bile acid metabolism

Published: 15 August 2022| Version 2 | DOI: 10.17632/przhxygkkm.2
Contributor:
Danqi Wang

Description

We used 16S rRNA sequencing with bile acid metabolomics to find that GEB extract (GEBE) improved the intestinal microbiota and increased serum secondary bile acid levels in high-fat diet (HFD)-induced mice, as well as GLUT4 expression on white adipose tissue (WAT) and improved insulin resistance in the organism.

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Institutions

Yanbian University

Categories

Pharmacy, Bile Acid Metabolite, Gut Microbiome

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