Bacterial isolates cultured from various sampling sites in patients with chronic rhinosinusitis
Description
This is a dataset that accompanies the paper "Challenging the gold standard: methods of sampling for microbial culture in patients with chronic rhinosinusitis". It contains the results of culture from samples obtained from 50 patients with chronic rhinosinusitis. The samples (swabs and tissue biopsies) were collected during endoscopic sinus surgery from the middle nasal meatus, maxillary sinus and frontal sinus. Additionally, swabs were taken from the nasal vestibule. The bacterial isolates were identified and tested for antibiotic susceptibility. The data shows that the results differ between sampling sites. The middle nasal meatus is not a representative sampling site for the sinuses as a whole. Multiple swabs were required to capture all culturable pathogens, while invasive biopsies usually do not provide additional information. Abbreviations: E - erythromycin DA - clindamycin NA - nalidixic acid IMP - imipenem MEM - meropenem ETP - ertapenem AK - amikacin CN - gentamicin NET - netilmicin TOB - tobramycin AMC - amoxicillin/clavulanic acid CXM - cefuroxime CTX - cefotaxime CAZ- ceftazidime FEP - cefepime CIP- ciprofloxacin TIC- ticarcillin TIM - ticarcillin/clavulanic acid PRL - piperacillin TZP - piperacillin/tazobactam SXT - trimethoprim sulfamethoxazole
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Steps to reproduce
The methodology was described in: J. Szaleniec, A. Gibała, M. Pobiega, S. Parasion, J. Składzień, P. Stręk, T. Gosiewski, M. Szaleniec, "Exacerbations of Chronic Rhinosinusitis— Microbiology and Perspectives of Phage Therapy", Antibiotics, 8 (2019) 175