ACGV as a predictor of adverse perinatal outcomes in SGA fetuses
Description
This is the dataset of a single-center retrospective cohort study of all singleton pregnancies with small-for-gestational-age fetuses diagnosed and delivered at a quaternary institution. The objective was to assess the predictive value of abdominal circumference growth velocity (ACGV) between the second and third trimesters to predict adverse perinatal outcomes in a cohort of small-for-gestational-age fetuses without evidence of placental insufficiency (i.e., fetal growth restriction). Crude and adjusted odds ratios (ORs) and corresponding confidence intervals (CIs) were calculated via logistic regression models to assess the potential association between abnormal ACGV (i.e., <10th centile) and adverse perinatal outcomes defined as a composite outcome (i.e., umbilical artery pH <7.1, 5-minute Apgar score <7, admission to the neonatal intensive care unit, hypoglycemia, intrapartum fetal distress requiring expedited delivery, and perinatal death). Furthermore, the area under the receiver-operating characteristic curve (AUC) of 3 logistic regression models based on estimated fetal weight and ACGV for predicting the composite outcome was also calculated. A total of 154 pregnancies were included for analysis. The median birthweight for the cohort was 2,437g (interquartile range [IQR] 2280, 2635). Overall, the primary composite outcome was relatively common (29.2%). In addition, there was a significant association between abnormal ACGV and adverse perinatal outcomes (OR 3.37, 95% CI 1.60, 7.13; adjusted OR 4.68, 95% CI 1.93, 11.38). Likewise, the AUC for the ACGV was marginally higher (0.64) than the estimated fetal weight (0.54) and ACGV + estimated fetal weight (0.54). Still, no significant difference was detected between the curves (P=0.297).