Demystifying excess immune response in COVID-19 to reposi-tion an orphan drug for down-regulation of NF-κB: A systematic review

Published: 14 January 2021| Version 1 | DOI: 10.17632/r6xnwwwrhz.1
Manish Gehani, Apparao Peddapalli, Arunasree Kalle, Siva Peddapalli, Angela Peter, Shashwat Sharad


Screening, Risk of Bias Assessment, and Data Extraction for the Systematic Review.


Steps to reproduce

Pubmed was searched for free full articles not related to therapeutics or co-morbid sub-groups, published in English until 27.10.2020, irrespective of type of article, country, or region. Keywords: (Covid-19 OR SARS-CoV-2 OR nCoV OR "Novel Corona") AND ("excess immune response" OR "exaggerated immune response" OR "excessive immune response" OR "excess immunity" OR "exaggerated immunity" OR "excessive immunity" OR "hyperinflammation" OR "excess inflammation" OR "exaggerated inflammation" OR "excessive inflammation") NOT ("clinical trials" OR "clinical trial" OR "trial")


Immunology, COVID-19