Proteomic analysis of senescent and non-senescent CHME-5 microglia.

Published: 12-10-2019| Version 2 | DOI: 10.17632/rcb56r2rvh.2
Luís Marques,
Adiv Johnson,
Alexandra Stolzing


In this experiment, senescent CHME-5 microglial cells were generated and their proteomes were compared to non-senescent CHME-5 microglial cells. Compared to non-senescent cells, a detailed proteomic analysis using SWATH-MS identified 201 proteins that were significantly downregulated and 127 that were significantly upregulated in senescent cells.