A receptor-independent, data-driven framework for broad-spectrum phage cocktails against vancomycin-resistant Enterococcus faecium

Description

Table S1 Phages included in this study. Table S2 Enterococcus strains included in this study. Table S3 The score of phage infection network on Enterococcus strains with spot assay. Table S4 Information on the mutation sites of the phage-resistant strains. Table S5 Plasmids and primers for complemented strain construction. Table S6 Antibiotic sensitivity profile of the phage-resistant strains. Table S7 Pairwise phage co-infection assays across 6 strains. Table S8 Information of candidate phage cocktail library. Table S9 Inhibition rates of 16 phage cocktails against 157 E. faecium strains. Table S10 Analysis of non-inhibition of discordant strains (theoretically susceptible, actually resistant) by phage cocktails (k=6).

Institutions

• Linyi University

  Shandong, Linyi

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