Theoretical, Cultural, and Perceptual Correlates of Human Papillomavirus Vaccine Acceptance (HPV-VA) and Vaccine Uptake (HPV-VU) in a Hispanic Community

Published: 10 November 2022| Version 1 | DOI: 10.17632/rg58w44khr.1
Gabriel Frietze


A survey was administered to a community sample of adults aged 18-65 years residing in El Paso, Texas. Survey questions explored theoretical perceptual, and cultural factors that were hypothesized to be associated with HPV-Vaccine Acceptance (HPV-VA) and HPV-Vaccine Uptake (HPV-VU) among the predominately Hispanic population in this region. The purpose of the current study was to examine theoretical (i.e., the Health Belief Model), perceptual (e.g., trust and recommendations from an HCP), and cultural (e.g., language, household size, familism, and religiosity) influences of HPV-VA and HPV-VU in predominately Hispanic community. We hypothesize that theoretical, perceptual, and cultural factors will be associated with HPV-VA and HPV-VU. Specifically, perceived effectiveness, perceived safety, and perceived severity will be positively associated with HPV-VA and HPV-VU; in contrast, perceived harm will be inversely associated with HPV-VA and HPV-VU. We also predicted that one’s family’s attitudes about vaccines would be positively associated with one’s own attitudes about vaccines. Moreover, we explored the role of trust, HCP recommendations, and culture. This research was supported by the National Institute on Minority Health and Health Disparities of the National Institutes of Health under Award Number U54MD007592. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.


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The author conducted a series of analyses within the data set. First, the author excluded participants who failed the attention check item (as indexed as "attention" in the data set. Nineteen participants were excluded for this reason. Six-hundred and two adults (Mage = 34.65, SD = 9.79) remained. Next the author calculated reliability estimates for each of the measures included. The author then ran descriptives and frequencies of all variables to create demographic and background tables. Correlation analyses examined continuous variables and chi-square analyses examined categorical variables. Logistic regression examined predictors of vaccine uptake (yes=1, no =0) and linear regression examined predictors vaccine acceptance. The author examined associations between family attitudes about vaccines and individual attitudes about vaccines. Additionally, the author examined factors such as culture and trust.


University of Texas at El Paso


Vaccine, Human Papillomavirus, Attitude and Beliefs, Trust in Health Care Services


National Institutes of Health