Desterke et al, 2020, Heterogeneity of macrophage immunoproteasome activation during lung COVID19 disease

Published: 09-11-2020| Version 1 | DOI: 10.17632/rjmyz3j52y.1
Contributor:
christophe desterke

Description

This study describe the activation of immunoproteasome components in M1 polarized macrophages at lung level during COVID19 disease. - Supplemental table 1:Table of genes implicated in MHC class I antigen presentation and found up regulated in COVID19 lung depending of SARS-COV2 virus level detected in the tissue - Supplemental Table 2: Genes found to be significant on PSMB8 cell trajectory inside CD14+/CD68+ bronchoalveolar cells from COVID19 patients - Supplemental Table 3 : Table of allele prevalence for 70 most frequent HLA-A,B,C through 20 ethnicities with worldwide distribution (USA NMDP bone marrow registry) - Supplemental Table 5: SARS-COV2 immunopeptidome against MHC class I presentation through 70 most prevalent HLA-A,B,C alleles

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Steps to reproduce

these data are connected to the associated manuscript but also with the bioinformatics code provided at the following address: https://github.com/cdesterke/covid19if