Modified red light 5-aminolevulinic acid photodynamic therapy versus low dose isotretinoin therapy for moderate to severe acne vulgaris: A prospective, randomized, multicenter study
Description
Supplemental materials of the article of Journal of the American Academy of Dermatology: "Modified red light 5-aminolevulinic acid photodynamic therapy versus low dose isotretinoin therapy for moderate to severe acne vulgaris: A prospective, randomized, multicenter study". Supplementary figure 1. A) The overall effective rate of comedones, papules, pustules, cysts, and nodules in one-month post-therapy. B) The IGA scores in the two groups at baseline and in one-month post-therapy. C) Time to achieve 50% lesion improvement (T50) in two groups. ns no significant difference, **P<0.01, ***P<0.001. Supplementary figure 2. Typical pictures of the cases in the M-PDT and the ISO groups before and after the therapy. The lesions in the M-PDT group showed clear improvements by week-4 and the improvement was sustained until 6-mon post-therapy. Better skin texture was also observed. The ISO group showed a transient exacerbation at week-4, followed by marked improvement at 1-mon post-therapy, which was sustained until 6-mon post-therapy.