C. molle data J Ngwisha
Description
Research Hypothesis Combretum molle extracts possess significant antibacterial properties. Data Overview Collected data includes antibacterial activity of various C. molle extracts tested against pathogens like S. aureus, E. coli, and P. aeruginosa. Parameters include susceptibility, MIC values, and statistical analyses. Data Collection Method Extract Preparation: Hexane, Ethyl Acetate: Hexane, DCM, and Ethanol extracts. Antibacterial Testing: Tested against pathogens. Susceptibility Testing: Categorized as Susceptible (S), Intermediate (I), or Resistant (R). Notable Findings Hexane and DCM Extracts: Significant antibacterial activity. Variability: Different pathogens show varying susceptibility to extracts. Interpretation Combretum molle extracts show potent antibacterial properties, with notable variability across pathogens. Detailed Summary ODs and Suscept DCM & Ethanol: OD and susceptibility data (241 rows). C. molle MIC Data: MIC values for different extracts (19 rows). C. molle vs tetracycline ANOVA: ANOVA comparing efficacy with tetracycline (14 rows). C. molle Paired TTest: Paired T-Test results (13 rows). Cidal_Static Data: Bactericidal vs. bacteriostatic results (23 rows). PILOT RUN- ETHANOL EXTRACTS: Preliminary ethanol extract data (26 rows). EXHAUSTIVE EXTRACTIONS DATA: Detailed extraction procedures (22 rows). Conclusion Combretum molle extracts, especially Hexane and DCM, exhibit strong antibacterial effects, supporting further research and potential clinical applications.
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In this study, a solvent based panel of extracts of C. molle was assessed for antimicrobial activity against select antimicrobial-resistant (AMR) priority pathogens. We commenced by quantifying the extract yield from each of the four solvents used for the exhaustive extraction that would facilitate subsequent dilutions. Thereafter, we investigated the antimicrobial activity of the various solvent extracts of the Combretum molle leaf powder and qualitatively determined the phytochemical composition of the extracts. The extracts’ bioactivity was assessed against WHO priority list AMR bacterial pathogens to determine comparative susceptibility