Single-cell stress-marker staining intensities in B220⁺ B cells from MASH-driven hepatocellular carcinoma mice under chow, MASH, and MASH phenylalanine-free diet conditions
Published: 23 July 2026| Version 2 | DOI: 10.17632/s8vj25dzzx.2
Contributor:
Liuqing YangDescription
Per-cell fluorescence intensity values for six multiplexed markers (B220, p-PASK, p-JNK, p-S6, p-AMPK, p-eIF2α) measured in B220⁺ B cells across three dietary conditions (chow, MASH, MASH Phe-free) by high-throughput spatial protein imaging. Data support Figure 6 of A phenylalanine–stress response axis controls tertiary lymphoid structure maturation and checkpoint immunotherapy efficacy. Tab 1: Opal channel-to-target annotation. Tabs 2–4: per-object intensity values for each condition.
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Institutions
- The University of Texas MD Anderson Cancer CenterTexas, Houston
Categories
B Cell, Hepatocellular Carcinoma, Non-Alcoholic Fatty Liver Disease, Phenylalanine, Cellular Stress Response, Spatial Transcriptomics, Spatial Metabolomics