Neckel et al CatWalk and RAGT data

Published: 29 April 2021| Version 1 | DOI: 10.17632/sg3d7dv345.1
Contributor:
Nathan Neckel

Description

Our group strives to restore overground locomotion following spinal cord injuries through the use of robot-assisted gait training (RAGT) . Specifically, following a C4/5 over-hemisection injury, we train young adult female rats in the Robomedica Rodent Robotic Motor Performance System (RRMPS) for 4 weeks. We assess their performance within the device, as well as any changes in unassisted overground locomotion with the CatWalk gait analysis device. The MATLAB data provided here contains the raw RRMPS output, and select CatWalk variables (x/y position, initial contact/ toe-off time) from all rats, from all groups, from all studies. For more details, please see the following papers; Neckel ND, Dai HN, Burns MP. A novel multidimensional analysis of rodent gait reveals the compensation strategies employed during spontaneous recovery from spinal cord and traumatic brain injury. J of neurotrauma. 2018 Oct 20(ja). Neckel ND. Novel spatiotemporal analysis of gait changes in body weight supported treadmill trained rats following cervical spinal cord injury. J Neuroeng Rehab. 2017; 14(1):96. Neckel ND. Methods to quantify the velocity dependence of common gait measurements from automated rodent gait analysis devices. J Neurosci Methods. 2015 Sep 30;253:244-53. Neckel ND, Dai H, Bregman BS. Quantifying changes following spinal cord injury with velocity dependent locomotor measures. J Neurosci Methods. 2013 Mar 30;214(1):27-36.

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Georgetown University Biomedical Graduate Research Organization

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Health Sciences

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