Proteomics output data for "Two independent respiratory chains adapt OXPHOS performance to glycolytic switch" by Fernandez-Vizarra et al. (2022).

Published: 12 September 2022| Version 2 | DOI: 10.17632/spsg756sx8.2
Contributor:
Erika Fernandez-Vizarra

Description

The files contain proteomics output datasets associated with the manuscript entitled: "Two independent respiratory chains adapt OXPHOS performance to glycolytic switch" by Fernandez-Vizarra et al. (2022). The first file (data for Figure 3A) is the result of a SILAC-based quantitative proteomics analysis on mitochondria from HEK 293T SCAFI-KO, COX7A2-KO and DOUBLE-KO in comparison with WT cells. The other two files contain peptide intensity maps and hierarchical clustering analysis derived from Complexome Profiling experiments (native electrophoresis separation followed by mass spectrometry) performed in two human postmitotic tissues, I.e, brain fronatal cortex and skeletal muscle. These data were used to create Figures 4A and 4B, respectively.

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Institutions

Universita degli Studi di Padova Dipartimento di Scienze Biomediche, Hospital Universitario 12 de Octubre, University of Melbourne Bio21 Molecular Science and Biotechnology Institute, University of Cambridge, MRC Mitochondrial Biology Unit

Categories

Respiratory Chain, Expression Proteomics

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