Endothelial cells under therapy-induced senescence secrete CXCL11, which increases aggressiveness of breast cancer cells

Published: 22 October 2019| Version 1 | DOI: 10.17632/sr73bv5rx8.1
Contributor:
Hyun Jung Hwang

Description

SASP from endothelial cells experiencing therapy-induced senescence promotes the aggressive behavior of cancer cells, and that CXCL11 could potentially be targeted to prevent the adverse effects of therapy-induced senescent endothelial cells on the tumor microenvironment.

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Institutions

Inha University College of Medicine

Categories

Cellular Senescence

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