Virological and Immunological Features of Sars-CoV-2 Infected Children Who Develop Neutralizing Antibodies

Published: 26 January 2021| Version 1 | DOI: 10.17632/stxwzbyfsc.1
Contributors:
Nicola Cotugno, Alessandra Ruggiero, Giuseppe Rubens Pascucci, Paolo Palma

Description

CD40L - CovPosST.xlsx, CD40L - CovPosUS.xlsx and Bcells - CovPosUS.xlsx datasets were used in the Correlation.R script to produce Supplementary Fig. 4 and by Mofa.R script to produce Figure 5 and Supplementary Fig. 5. Olink_KD.csv dataset (proteomic Olink NPX values) was used in the Correlation.R script to produce Figure 4e, 4f and Supplementary Fig. 4, and by Mofa.R script to produce Figure 5 and Supplementary Fig. 5. 20200902 metadati PRNT.txt dataset was used in the Correlation.R script to produce Figure 1e, Figure 4e, Figure 4f and Supplementary Fig. 4; by AUC_NP_swabs.R to calculate the AUC values and by Mofa.R to produce Figure 5 and Supplementary Fig. 5. Dataset Time-Matched 1.txt dataset was used in the Correlation.R script to produce Figure 1a-d. Dataset Time-Matched 2.txt dataset was used in the Correlation.R script to produce Supplementary Fig. 1. CT – NP.txt dataset was used in AUC_NP_swabs.R to calculate the AUC values. supp figures_dataset.xlsx dataset was used to produce the Fig. 2b, Fig 2d, Fig 3a, Fig. 3b, Fig. 3c, Fig. 3d using the software prism graphpad. dataset table I.xlsx was used to produce the table 1, using the software prism graphpad. Finally, the datasets Fig 1f.xlsx, Fig 2.xlsx (Fig 2b, Fig 2c), Fig 3.xlsx (Fig. 3b, Fig. 3c) and Fig 4.xlsx (Fig 4a-d) was used to produce the homonymous figures using graphpad.

Files

Steps to reproduce

Project is created with RStudio (version 3.6.2) and Graphpad Prism 8 software

Categories

Immunology, Clinical Study, Neutralizing Antibody, Severe Acute Respiratory Syndrome Coronavirus 2, COVID-19

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