Data for: Comparison of parameters affecting GNP-loaded choroidal melanoma dosimetry; Monte Carlo study

Published: 3 February 2018| Version 2 | DOI: 10.17632/sv8gms2fdn.2
Marjan Sharabiani, Amir Rahnamai Barghi, somayeh asadi, Mehdi VAEZ-ZADEH


The results of our study indicate the significance of using a full Monte Carlo model of human eye globe instead of water phantom for the sake of precise ophthalmic dosimetry in the presence of GNPs. The significance of GNPs’ size effect on macroscopic dose enhancement in choroidal melanoma was also demonstrated, with implications on larger diameter GNPs in combination with a high concentration depositing more energy on a macroscopic level. This study also specifies the efficacy of low energy photon sources in the presence of GNPs in yielding a high dose to the region of interest. Experimental works on a wide range of sizes and concentrations of GNPs is a prerequisite in the precise brachytherapy treatment of choroidal melanoma which will be conducted in future studies.



Nanoparticles, Brachytherapy, Monte Carlo Simulation, Gold