APPswe mice
Description
File name: Activity_5to11months Activity data acquired using telemetry are reported for APPswe and WT mice; values were obtained by averaging the values over a recording period of three days. Mice of the two groups are reported in different columns. Each row contain the average values of activity for 5 min intervals. Data starts at 8PM when lights go ON (inactive phase), until the end of the active phase (i.e. time span of the data is 24h) File name: Temperature_5to11months Temperature data acquired using telemetry are reported for APPswe and WT mice; values were obtained by averaging the values over a recording period of three days. Mice of the two groups are reported in different columns. Each row contain the average values of body temperature for 5 min intervals. Data starts at 8PM when lights go ON (inactive phase), until the end of the active phase (i.e. time span of the data is 24h)
Files
Steps to reproduce
Telemetry TA-F10 transmitters (Data Sciences International) allow the simultaneous acquisition of locomotor activity and core body temperature in freely moving animals via receivers located below the individual mouse cages (locomotion measurements are based on the changes in signal strength of the implanted telemetry device relative to its receiver). The transmitter signals were acquired via a computer, connected to the individual receivers through intermediary matrix interfaces, and integrated using Ponemah software (Data Sciences International). Transmitters were switched on/off using a magnet immediately before/after testing. We used telemetry to measure the circadian profile of locomotion and body temperature in the home cage at 5, 7, 9 and 11 months of age. A scheduled acquisition mode (20 seconds of recording/minute) was used to assess the circadian profile of locomotion and body temperature; recording at each age was performed over 3 days (72 hours) and data were averaged across the three days to represent a single 24 circadian cycle for each mouse. We extracted the 5 min-bins average values.