Cross-Sectional Characteristics of Pediatric-Onset Discoid Lupus Erythematosus: Results of a Multicenter, Retrospective Cohort Study
This file details supplementary data for the JAAD paper "Cross-Sectional Characteristics of Pediatric-Onset Discoid Lupus Erythematosus: Results of a Multicenter, Retrospective Cohort Study." This file includes demographics for the 17 sites that enrolled patients across North America and Canada, including the number of patients screened and number who met eligibility criteria for the study. In this cohort, patients with pediatric onset DLE + SLE were most likely to be adolescents, with SLE diagnosis solidified by positive serologies and/or the presence of end-organ damage. In adolescence, diagnosis of DLE should prompt thorough screening for SLE including referral to rheumatology
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This retrospective observational cohort study was conducted at 17 clinical sites and was approved by each site’s Institutional Review Board (IRB) with the University of Wisconsin as the coordinating center. Site demographics are listed here in the supplementary data. Electronic medical records from January 1, 1997 to December 31, 2018 were searched using the ICD 9/10 diagnosis codes for discoid lupus (605.4, L93, L93.2). Patients followed by pediatric dermatology, pediatric rheumatology, or both, with age < 18 years at diagnosis of DLE were included. Exclusion criteria included insufficient documentation or clinical and/or histopathologic findings inconsistent with DLE.