Antiviral activity of Ugandan medicinal plants against human immunodeficiency virus type-1 (HIV-1)

Published: 23 December 2022| Version 1 | DOI: 10.17632/v55397mdpk.1
Contributors:
Godwin Anywar,
,
,
,

Description

This data set describes data on the antiviral activity of 11 medicinal plant species used to treat people people living with HIV/AIDS in Uganda against-HIV-1. The data was generated from 22 plant extracts were tested against HIV-1 Pseudovirions (PV) HXB2 (IIIB) strain using the human glioblastoma cell line; U87.CD4.CXCR4, transfected with the luciferase firefly reporter gene. The selective inhibition of the growth of HIV-1 PV was measured using the selectivity index. The in vitro cytotoxicity of each of the plant extracts was also evaluated using the AlamarBlue cell viability assay on U87.CD4.CXCR4 cells. The experiments were conducted at the Institute for Medical Microbiology & Virology, University Clinics & Faculty of Medicine, University of Leipzig, Germany and the Fraunhofer Institute for Cell Therapy & Immunology, Leipzig, Germany

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Categories

Molecular Biology, Ethnopharmacology, Antiviral Activity, Medicinal and Aromatic Plants, Ethnobotany

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