Diospyros kaki

Published: 1 October 2024| Version 1 | DOI: 10.17632/v5t74bk9dg.1
Contributor:
Mrinal Sharma

Description

The behavioural and biochemical assesment results are mentioned with graphs in the excel sheet. In rats with stress-induced depression, both the extracts of ethanol (200 mg/kg) and aqueous (200 mg/kg) given orally showed improvement in depressive symptoms. These benefits were evidenced by a significant (P<0.05) decrease in immobility time in both the tail suspension and the forced swimming tests, a significant (P<0.05) increase in sucrose consumption in the sucrose preference test, and a rise in rearing and crossing during the test in the open field. Furthermore, the extracts led to decreased levels of monoamine oxidase A and B (P0.05), reduced MDA levels (P0.05), and improved superoxide dismutase and Glutathione-S-transferase activity when compared with CUS depressive rats and the standard treatment Impramine (15 mg/kg).

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