Cardiomyocyte transcriptome remodeling in response to Trypanosoma cruzi infection
Published: 18 September 2023| Version 2 | DOI: 10.17632/v82vdkt7ws.2
Contributors:
Katherine Candray, Yu NakagamaDescription
HL-1 rodent cardiomyocytes were infected with T. cruzi trypomastigotes of the Colombian, Y or Tulahuen strain. RNA was serially isolated post-infection for microarray analysis. Genes with signals above the threshold of 43, 48, 43, 52 at 24 and 48 hours on the T cruzi-infected (CCM model) and control conditions, respectively, were excluded leaving 11,041 and 11,000 valid gene probes for analysis. "24h_48h_ValidGenes_q_Values.xlsx" file was added containing the P-values adjusted by multiple comparisons (q-values).
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Categories
Gene Expression, Microarray, Cardiomyocyte, Trypanosoma cruzi
Funding
Japan Agency for Medical Research and Development
JP21jm0110016
Japan Agency for Medical Research and Development
JP21wm0325049
Japan Society for the Promotion of Science
19K23992