Mitochondrial Microhomology-Mediated End Joining (MMEJ) and DNA Delivery Data
Description
A full description of the data can be found in our bioRxiv preprint: Maximov V.V., Shebanov N., Nikitchina N., Rapoport R., Maor Y., Tarassov I., Pines O., Entelis N. (2025) Mitochondrial genome microhomology-mediated editing by donor DNA delivery into mitochondria in human cells. bioRxiv, doi: https://doi.org/10.1101/2025.11.02.686110, https://www.biorxiv.org/content/10.1101/2025.11.02.686110v1. Figures, where the data are shown, can be seen in the names of the data files. Files "Fig 2C - Gel 1.tif", "Fig 2C - Gel 2.tif", "Fig 2D - Gel 3.tif", and "Fig 2D - Gel 4.tif" are images of gels, which correspond membranes on figures 2C and 2D. A description of the files "Fig 2C - Gel 1.tif", "Fig 2C - Gel 2.tif", "Fig 2D - Gel 3.tif", and "Fig 2D - Gel 4.tif" can be seen in the Word file "Unprocessed Fig 2C&D-Gels Description.docx". The scn-format files, which names start from "Fig 2S", present original Western blot data of MGME1, AsCas12a, and β-Actin expression in samples, which are described in Figure 4 of the above mentioned bioRxiv preprint. A description of the scn-format files, which names start from "Fig 2S", can be seen in the Word file "Description of Unprocessed Figure 2S Images.docx".