Predictors of Mortality Among Hemodialysis Patients at Al-Thora General Hospital, Ibb Governate, Yemen: A Retrospective Study
Description
A retrospective study involving 4194 HD patients in the Nephrology Center of Al-Thora General Hospital, Ibb Governate, Yemen between March 2017 and January 2024. The data on demographic characteristics, risk factors, and comorbidities of HD patients were gathered and analyzed. The Kaplan-Meier test and the log-rank test were used to evaluate and compare survival curves and the proportional Cox hazard model was used to investigate the factors associated with mortality.
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Study design and population: A retrospective study involving 4194 HD patients in the Nephrology Center of Al-Thora General Hospital, Ibb Governate, Yemen between March 2017 and January 2024 for 8 years. The primary outcome was death and all patients were monitored until death or censoring (end of follow-up, loss of follow-up, transfer, or kidney transplant). Data were gathered from patients' medical records as well as the computerized record system at our facility in Al-Thora General Hospital, Ibb Governorate, Yemen. This center is the only one in the region and serves HD patients in Ibb Governorate. Furthermore, since 2015, it has covered additional HD patients, including Taiz Governate and other Governates that stopped or did not operate owing to restrictive policies during the present conflicts [9,10]. Exclusion criteria: Patients on chronic dialysis for less than 3 months, those with cancer at the time of inclusion, and pregnant women were excluded. Collected data: Demographic characteristics such as age, age classes (< 65, ≥ 65 years), gender, residency (rural or urban), city (Taiz Governate, Ibb Governate, or other cities), comorbidities such as hypertension, thyroid disease, diabetes mellitus (DM), cardiovascular disease, cerebral vascular accident, viral hepatitis infections with virus C and B, and chronic liver disease, and outcome (live or death) were collected from the patient's medical record. The causes of death were identified by differentiating deaths directly related to CKD, from those caused by other causes. Main outcome: The primary outcome was recording the mortality. The secondary outcome was the predictive factors of mortality among HD patients.